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568例HBsAg携带者进行肝活检,标本用福尔马林固定并用免疫荧光技术检测δ抗原。部分病人还作了肝标本冰冻切片,对同一份标本的固定与冰冻切片均检测肝内δ抗原,后者尚检测肝内HBcAg。结果 HBsAg携带者568例中137(男111,女26)例肝内δ抗原阳性,以21~40岁者阳性率最高。组织学检查均显示慢性肝炎;慢性持续性肝炎和慢性小叶性肝炎各6例,慢性活动性肝炎93例,慢性活动
568 HBsAg carriers were subjected to liver biopsy. The specimens were fixed in formalin and the δ antigen was detected by immunofluorescence. Some patients also made frozen sections of liver specimens, the same specimen fixed and frozen sections were detected in liver δ antigen, which is still testing the intrahepatic HBcAg. Results Of the 568 HBsAg carriers, 137 (111, 26) had positive intrahepatic δ antigen, with the highest positive rate in 21-40 years old. Histological examination showed that chronic hepatitis; chronic persistent hepatitis and chronic lobular hepatitis in 6 cases, 93 cases of chronic active hepatitis, chronic activity