论文部分内容阅读
Objective:To evaluate the clinical significance of platelet(PLT) count in epithelial ovarian cancer,and to inves-tigate the correlation between thrombocytosis and the incidence of epithelial ovarian cancer.Methods:We evaluated 220 epithelial ovarian tumor patients divided into early stage epithelial ovarian cancer group(n = 80),advanced stage epithelial ovarian cancer group(n = 50) and benign ovarian tumor group(n = 90) as controls,who underwent primary surgical treatment.Three groups were evaluated with the relationship between platelet counts and preoperative and postoperative CA125,histo-pathology,abdominal edema,residual tumor,and lymph node metastasis.Epithelial ovarian cancer patients were evaluated whether platelet count was decreased after surgery.Results:The mean platelet counts were(234.55 ± 71.51) x 109/L in the early stage epithelial ovarian cancer group,(308.12 ± 111.95) x 109/L in the advanced stage epithelial ovarian cancer group,and(206.28 ± 52.62) x 109/L in the benign ovarian tumor group,with a significant difference among the 3 groups(P < 0.05).In the early stage epithelial ovarian cancer group,the platelet count was correlated with histopathology.In the advanced stage epithelial ovarian cancer group,there was a correlation between thrombocytosis and the incidence of that residual tumor diameter was greater than 2 cm.But there was no relationship between platelet count and histopathology,CA125,abdominal edema,or lymph node metastasis.In general the platelet count was decreased after surgery.Conclusion:An increased platelet count is commonly seen in patients with epithelial ovarian cancer,but it usually decreases after surgery.Patients with thrombocytosis have poor prognosis.Platelet count can be used as a marker for the development and prognosis of epithelial ovarian cancer.
Objective: To evaluate the clinical significance of platelet (PLT) count in epithelial ovarian cancer, and to in-tigate the correlation between thrombocytosis and the incidence of epithelial ovarian cancer. Methods: We evaluated 220 epithelial ovarian tumor patients divided into early stage epithelial ovarian cancer group (n = 80), advanced stage epithelial ovarian cancer group (n = 50) and benign ovarian tumor group (n = 90) as controls, who underwent primary surgical treatment. Three groups were evaluated with the relationship between platelet counts and preoperative and postoperative CA125, histo-pathology, abdominal edema, residual tumor, and lymph node metastasis. Epithelial ovarian cancer patients were evaluated for platelet count was decreased after surgery. Results: The mean platelet counts were (234.55 ± 71.51) x 109 / L in the early stage epithelial ovarian cancer group, (308.12 ± 111.95) x 109 / L in the advanced stage epithelial ovarian cancer group, and (206.28 ± 52.62) x 109 / L in the ben ign ovarian tumor group, with a significant difference among the 3 groups (P <0.05). In the early stage epithelial ovarian cancer group, the platelet count was correlated with histopathology. In the advanced stage epithelial ovarian cancer group, there was a correlation between thrombocytosis and the incidence of that residual tumor diameter was greater than 2 cm. There was no relationship between platelet count and histopathology, CA125, abdominal edema, or lymph node metastasis. In general the platelet count was decreased after surgery. Confclusion: An increased platelet count is commonly seen in patients with epithelial ovarian cancer, but it that normally falls after surgery. Patients with thrombocytosis have poor prognosis. Platelet count can be used as a marker for the development and prognosis of epithelial ovarian cancer.