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目的观察更昔洛韦联合平胃散加味治疗婴儿巨细胞病毒性肝炎的临床疗效。方法 58例婴儿巨细胞病毒性肝炎患儿随机分为2组:A组予更昔洛韦治疗,B组予更昔洛韦+平胃散加味治疗,观察两组患儿的临床疗效。结果 B组总有效率(89.7%)明显高于A组(72.4%);B组血清总胆红素恢复时间(50.86±7.78)d,ALT的恢复时间(41.54±4.12)d,均明显短于A组的(70.47±10.62)d和(47.74±5.92)d,两组比较有显著性差异(P<0.05或P<0.01)。结论平胃散加味联合更昔洛韦治疗婴儿巨细胞病毒性肝炎能有效促进肝细胞功能恢复,消退黄疸,缩短病程。
Objective To observe the clinical efficacy of ganciclovir combined with Pingwei San in the treatment of infant cytomegalovirus hepatitis. Methods Fifty-eight infants with cytomegalovirus hepatitis were randomly divided into two groups: group A treated with ganciclovir, group B treated with ganciclovir + pingweisan, and the clinical effects of both groups were observed. Results The total effective rate (89.7%) in group B was significantly higher than that in group A (72.4%). The serum total bilirubin recovery time (50.86 ± 7.78) d and ALT recovery time (41.54 ± 4.12) days in group B were significantly shorter There was significant difference between the two groups (P <0.05 or P <0.01) in group A (70.47 ± 10.62) d and (47.74 ± 5.92) d. Conclusion Pingweisan plus ganciclovir combined with ganciclovir in the treatment of infantile cytomegalovirus hepatitis can effectively promote the recovery of liver cells, fade jaundice and shorten the course of the disease.