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一项由美国国立卫生院(NIH)国家变态反应与传染性疾病研究所(NIAID)资助的研究结果显示,一些新型抗癌药物可使小鼠幸免于致死剂量的牛痘病毒(即天花病毒)而存活下来。该研究结果提示 Gleevec 或其它相类似的抗癌药物可抑制天花疫苗的毒副作用;以往传统的天花病毒疫苗由减活的牛痘病毒制取,因此不能用于免疫力低下的人群使用,除非这些人可能暴露于天花病毒的紧急情况。负责该项研究的 NIAID 专家 Anthony S.Fauci 博士强调指出,此项研究有助于阐明痘病毒脱离感染细胞的细胞器作用;同时还为通过靶向特殊宿主细胞分子而非病毒本身治疗滤过性病毒感染的观点提供了有利证据。
A study funded by the National Institute of Allergy and Infectious Diseases (NIH) National Institute of Allergy and Infectious Diseases (NIAID) showed that some novel anti-cancer drugs can save mice from lethal doses of vaccinia virus (ie, VARV) Survive. The results suggest that Gleevec or other similar anti-cancer drugs can inhibit the side effects of smallpox vaccine; in the past, the traditional smallpox vaccines were made from vaccinated vaccinia virus and therefore should not be used in people who are immunocompromised unless they An emergency that may be exposed to smallpox virus. Dr Anthony S. Fauci, an NIAID expert in charge of the study, emphasized that the study helps to elucidate the role of the poxvirus in the removal of organelles from infected cells and also in the treatment of viral-associated viruses by targeting specific host cell molecules rather than the virus itself The point of infection provided favorable evidence.