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本文冻干制备了3批细菌内毒素国家标准品候选品.以第3批细菌内毒素国际标准品(10/178)为基准,采用凝胶法、动态浊度法和动态显色法3种方法,组织了14家单位进行协作标定.通过比较3批候选品标定结果的精密性及对3种标定方法是否存在显著性差异,最终确定其中一批候选品为第8批细菌内毒素国家标准品,效价为9000EU/支,批号150800-201601.“,”In the present study,we aimed to establish the 8th National Standard of Endotoxin using three batches of proposed National Standard of Endotoxin.We co-calibrated the potency of the proposed preparations against the 3rd International Standard (10/178) using the gel-clot method,kinetic-turbidimetric test and kinetic-chromogenic test.A total of 14 laboratories participated in this collaborative study.By comparing precision of three approved candidates' calibration results and analyzing the differences among the three results from different methods,we ultimately selected one of candidates as 8th National Standard of Endotoxin,and its potency is 9000 EU/ampoule and lot is 150801-201601.