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目的:探讨吉西他滨联合卡培他滨治疗复发转移性胃癌的效果,找出最佳的治疗方案。方法:选取2013年10月至2015年8月我院收治的复发转移性胃癌患者共有92例,随机分为观察组和对照组各46例,观察组采用吉西他滨联合卡培他滨进行治疗,对照组采用奥沙利铂联合亚叶酸钙进行治疗,两组患者均治疗3-6个周期,对比两组患者的治疗效果。结果:观察组患者治疗总有效率为89.2%,对照组为67.4%,观察组治疗效果明显优于对照组,P<0.05,有统计学意义。结论:西他滨联合卡培他滨治疗复发转移性胃癌疗效可靠,安全性高,可耐受,有利于疾病控制。
Objective: To investigate the efficacy of gemcitabine combined with capecitabine in the treatment of recurrent metastatic gastric cancer and to find out the best treatment plan. METHODS: A total of 92 patients with recurrent metastatic gastric cancer who were treated in our hospital from October 2013 to August 2015 were randomly divided into observation group and control group. 46 cases were treated with gemcitabine and capecitabine in the observation group. The group was treated with oxaliplatin and leucovorin. Both groups were treated for 3 to 6 cycles and the treatment effects of the two groups were compared. Results: The total effective rate was 89.2% in the observation group and 67.4% in the control group. The treatment effect in the observation group was significantly better than that in the control group, P<0.05, with statistical significance. CONCLUSION: The combination of sitagine and capecitabine is effective, safe, tolerable, and beneficial for disease control in the treatment of recurrent metastatic gastric cancer.