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目的探讨不能明确意义的非典型鳞状上皮细胞(atypical squamous cells of undetermined significance,ASCUS)的临床意义及处理方式。方法分析320例ASCUS患者的组织病理学结果和阴道镜评估与镜下活检结果。结果组织病理学检查显示,慢性炎症占143例(44.69%)、CIN1级80例(占25.00%),CIN II级47例(14.69%),CINIII级(42例(13.12%),浸润癌8例(2.50%)。结论宫颈细胞学检查结果 ASCUS可能是发现高级别CIN的信号。为及时发现宫颈病变需对ASCUS患者进行阴道镜检,有必要的话进行HPV-DNA检查。
Objective To investigate the clinical significance and treatment of atypical squamous cells of undetermined significance (ASCUS). Methods The histopathological and colposcopic evaluation and microscopic biopsy findings of 320 ASCUS patients were analyzed. Results Histopathological examination showed that chronic inflammation accounted for 143 cases (44.69%), CIN1 grade 80 cases (25.00%), CIN II grade 47 cases (14.69%), CINIII grade 42 cases (13.12%), (2.50%) .Conclusion Cervical cytology results ASCUS may be a signal to find high-grade CIN.For the detection of cervical lesions colposcopy should be performed on ASCUS patients, HPV-DNA examination is necessary if necessary.