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本实验对昆明小鼠、ICR小鼠、NIH小鼠、BALB/C小鼠、CFW小鼠等5个品系小鼠感染相同数量和同一来源的人源型弓形虫虫株(KS-86)的易感性进行了初步研究。发现CFW小鼠,昆明小鼠和ICR小鼠较易感弓形虫;而NIH小鼠和BALB/C小鼠易感性稍差(P<0.01)。提示:不同品系小鼠对弓形虫的易感性与H-2型别的关联性值得进一步研究。
In this study, 5 strains of Kunming mice, ICR mice, NIH mice, BALB / C mice and CFW mice were infected with the same number of Toxoplasma gondii strains (KS-86) from the same source Susceptibility conducted a preliminary study. It was found that CFW mice, Kunming mice and ICR mice were more susceptible to Toxoplasma gondii; while NIH mice and BALB / C mice were less susceptible (P <0.01). Tip: different strains of mice to Toxoplasma gondii susceptibility and H-2 type of relevance worth further study.