论文部分内容阅读
香豆素类物质在植物中分布广泛,是豆香型香料的主要成份之一,常用于日用香精中。秦皮中的秦皮甲素,补骨脂中的补骨脂内酯,另外,双香豆素,6,7-二甲氧基香豆素,7,8-二甲氧基香豆素,6-羟基-7-甲氧基香豆素等均属香豆素类物质。目前国内多数是植物(绝大多数为中药)提取物中香豆素类物质的定性或定量分析。国外的文献则偏重于香豆素作为药物在生物体中的代谢机理和生理毒性。色谱检测中应用最多的仪器是高效液相色谱。国外还报道了几种特别的高效液相色谱改进技术:胶束电动毛细管技术,凝胶溶胶通道技术,直角纳米通道技术,二维技术。另外,液质联用技术,薄层色谱和柱色谱,超临界流体色谱法,气相色谱也可用于香豆素的检测。
Coumarins widely distributed in plants, is one of the main components of bean flavor spices, commonly used in daily flavor. Aesculin in cortex pectin, psoralen in psoralen, additionally, dicoumarin, 6,7-dimethoxycoumarin, 7,8-dimethoxycoumarin, 6 - hydroxy-7-methoxy coumarin, etc. are coumarins. At present, most of the plants (mostly Chinese herbal) extract of coumarin qualitative or quantitative analysis. Foreign literature is biased toward the metabolic mechanism and physiological toxicity of coumarin as an agent in the organism. The most widely used instrument in chromatographic detection is high performance liquid chromatography. Abroad also reported several special high performance liquid chromatography improvements: micellar electrokinetic capillary technology, gel sol channel technology, right angle nanochannel technology, two-dimensional technology. In addition, LC-MS, TLC and column chromatography, supercritical fluid chromatography, gas chromatography can also be used for coumarin detection.