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目的探讨急性脑梗死患者血清中白细胞介素-6(IL-6)水平的变化及临床意义。方法测定99例急性脑梗死患者和49名健康人的血清中IL-6的含量,按脑卒中患者临床神经功能缺损程度评分(NDS)标准对患者进行评分。结果脑梗死组血清中IL-6水平为(53.48±16.12)pg/L明显高于正常对照(2.31±0.56)pg/L,差异有统计学意义(P<0.01)。结论血清IL-6水平增高与脑梗死的发生有密切关系。
Objective To investigate the changes of interleukin-6 (IL-6) in serum of patients with acute cerebral infarction and its clinical significance. Methods Serum levels of IL-6 were measured in 99 patients with acute cerebral infarction and 49 healthy individuals. The patients were scored according to the NDS score of stroke patients. Results The serum level of IL-6 in cerebral infarction group was (53.48 ± 16.12) pg / L which was significantly higher than that of the normal control group (2.31 ± 0.56) pg / L, the difference was statistically significant (P <0.01). Conclusion The increase of serum IL-6 level is closely related to the occurrence of cerebral infarction.