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人工造成家兔桡骨缺损后植入同种异体的微孔和无微孔脱钙骨基质(PDBM、NPDBM)及微孔和无微孔表面脱钙骨(PSDB、NPSDB)等四种骨组织,手术后2、4、8、12周进行99mTc-MDP骨显像,并与X线平片及组织学变化相比较。结果表明,微孔制备有利于植入骨的新骨形成,加速植入材料的新骨替代;SDB具有与DBM相似的诱导成骨作用;核素骨显像对早期判断异体移植骨的成活情况是一种有效而首选的方法。
Artificial rabbits were implanted into four kinds of bony tissues such as allogeneic microporous and non-microporous demineralized bone matrix (PDBM, NPDBM) and microporous and non-microporous surface demineralized bone (PSDB, NPSDB) 99mTc-MDP bone imaging was performed at 2, 4, 8 and 12 weeks after surgery and compared with plain radiographs and histological changes. The results showed that micro-porous preparation was beneficial to the formation of new bone in the implanted bone and accelerated the replacement of new bone in the implanted material. SDB had the similar inducing osteogenesis effect to DBM. The radionuclide bone imaging was very useful in early judgment of the survival of the allograft bone Is an effective and preferred method.