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为探索间质抑制剂治疗慢性活动性肝病,我们曾于1972至1977年试用上海第三制药厂试制的D-青霉胺(以下简称青霉胺)治疗临床表现顽固的病例50例,现就疗程满2个月以上的38例小结讨论如下: 临床资料一、病例选择:38例中男性35例,女性3例,年龄21至60岁。慢性肝炎27例,其中慢性活动性肝炎19例(诊断、分型和疗效参考1973年上海市肝炎协作组标准:临床、生化和病程综合判断);合并肝硬化3例;慢性持续性肝炎8例。病程近1年至10年。用药前均持续3～
To explore the use of interstitial inhibitors in the treatment of chronic active liver disease, we tested 50 cases of stubborn clinical manifestations of D-penicillamine (hereinafter referred to as penicillamine) trial trial of Shanghai No. 3 Pharmaceutical Factory from 1972 to 1977, 38 cases of more than 2 months course of treatment summarized as follows: Clinical data First, the patient selection: 38 cases of males in 35 cases, 3 females, aged 21 to 60 years. Chronic hepatitis in 27 cases, of which 19 cases of chronic active hepatitis (diagnosis, classification and efficacy of reference to the Shanghai Municipal Collaboration in Shanghai in 1973 standard: comprehensive assessment of clinical and biochemical and disease); with cirrhosis in 3 cases; chronic persistent hepatitis in 8 cases . Course of nearly 1 year to 10 years. Before treatment continued for 3 ~