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[目的]全面了解周口市健康人群乙肝病毒感染状况及乙肝抗体保护水平,为下一步开展乙肝防治提供科学依据。[方法]2009年9月,在周口市所辖各县(市、区)抽取城乡部分1～18岁人群进行血清学调查。[结果]调查2449人,HBsAg阳性率为2.29%,其中1～4岁为1.28%,5～9岁为1.78%,10～14岁为2.14%,15～18岁为4.00%(P<0.01);各个县(市、区)为0.82%～3.29%(P>0.05);城区为1.35%,农村为2.75%(P<0.05)。抗-HBs阳性率为81.18%,其中1～4岁为90.22%,5～9岁为85.25%,10～14岁为80.92%,15～18岁为67.83%(P<0.01);各县(市、区)为74.58%～86.59%(P<0.05);城区为85.47%,农村为79.05%(P<0.01)。[结论]目前周口市1～18岁人群乙肝病毒感染水平较低,乙肝免疫水平较高。
[Objective] To comprehensively understand the status of hepatitis B virus infection and the antibody protection of hepatitis B in healthy population in Zhoukou City, and provide a scientific basis for further prevention and treatment of hepatitis B. [Method] In September 2009, serological investigation was conducted in all the counties (cities and districts) under the jurisdiction of Zhoukou Municipality to collect the urban and rural population aged 1 to 18 years. [Results] The positive rate of HBsAg was 2.29% in 2449 people, including 1.28% in 1-4 years old, 1.78% in 5-9 years old, 2.14% in 10-14 years old and 4.00% in 15-18 years old (P <0.01) ); 0.82% ~ 3.29% (P> 0.05) in all counties (cities and districts); 1.35% in urban areas and 2.75% in rural areas (P <0.05). The positive rate of anti-HBs was 81.18%, among which 90.22% were from 1 to 4 years old, 85.25% from 5 to 9 years old, 80.92% from 10 to 14 years old and 67.83% from 15 to 18 years old (P <0.01) (P <0.05). The urban area was 85.47% and the rural area was 79.05% (P <0.01). [Conclusion] At present, the level of hepatitis B virus infection is lower in people aged 1 ~ 18 in Zhoukou City, and the immunity level of hepatitis B is higher.