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目的:肾上腺皮质癌是临床上罕见,且恶性程度较高的肿瘤。本研究拟对其临床病理特征、长期预后及影响预后的因素进行分析。方法:2001年1月~2012年1月共有18例肾上腺皮质癌患者于我院行根治性肾上腺切除术,本研究回顾性分析这18例患者的临床病理特征、长期预后及影响预后的因素。结果:患者的中位年龄为48岁。18例肾上腺皮质癌患者的3年、5年和10年生存率分别为60%、48%和16%。单因素分析法显示肿瘤浸润程度及淋巴结转移与长期预后有关。结论:根治性切除术可为肾上腺皮质癌提供治愈的机会,肿瘤浸浸润程度及淋巴结转移是影响肾上腺皮质癌患者预后的重要因素。
Purpose: Adrenocortical cancer is a rare clinical and malignant tumor. This study intended to analyze its clinical and pathological features, long-term prognosis and prognostic factors. METHODS: From January 2001 to January 2012, 18 patients with adrenocortical carcinoma underwent radical adrenalectomy in our hospital. The clinical and pathological features, long-term prognosis and prognostic factors were retrospectively analyzed in 18 patients. Results: The median age of patients was 48 years. The 3-year, 5-year and 10-year survival rates of 18 adrenocortical carcinomas were 60%, 48% and 16%, respectively. Univariate analysis showed that the degree of tumor infiltration and lymph node metastasis and long-term prognosis. Conclusions: Radical resection can provide adrenal cortical cancer with the opportunity to cure. The degree of tumor infiltration and lymph node metastasis is an important factor affecting the prognosis of patients with adrenocortical carcinoma.