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目的：探讨荷 S180肉瘤小鼠血中丙二醛（ malondialdehyde,MDA）和超氧化物歧化酶（ superoxide dismutase,SOD）的变化规律，以及采用中华眼镜蛇毒（ naja naja atra venom,NNAV）进行治疗后对 MDA和 SOD的影响。方法：用 TBA比色法和放免均相竞争抑制法检测血中 MDA和 SOD 1，观察不同病期（种瘤后 5天， 10天和 15天）荷瘤鼠血中 MDA和 SOD 1的变化，以及用不同浓度 NNAV（ 2μ g/ml， 4μ g/ml和 8μ g/ml）治疗对荷瘤鼠血中 MDA和 SOD 1的影响。 结果：发现荷瘤鼠血 MDA增高（ P
Objective: To investigate the changes of malondialdehyde (MDA) and superoxide dismutase (SOD) in blood of mice with S180 sarcoma, and to treat them with naja naja atra venom (NNAV). Impact on MDA and SOD. METHODS: MDA and SOD 1 in blood were measured by TBA colorimetric assay and homogenous competitive inhibition of radioimmunoassay. Changes in MDA and SOD 1 in blood of tumor-bearing mice at different stages (5, 10 and 15 days after seeding) were observed. , and the effect of different concentrations of NNAV (2 μg/ml, 4 μg/ml, and 8 μg/ml) on the MDA and SOD 1 in the blood of tumor-bearing mice. Results: It was found that blood MDA in tumor-bearing mice increased (P