Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary inf

• 作 者: JIANG XinQuan ZHANG ZhenJie ZHUANG DongMing CARR Michael J. ZHANG RuiLing LV Qiang SHI WeiFeng
• 机 构: School of Public Health, Taishan Medical College,Institute of Pathogen Biology, Taishan Medical Coll
• 出 处: Science China(Life Sciences)
• 发表日期: 2015年07期
• 关键词: evolutionary indispensable phylogenetic Figure estimates clade length outbreak s

We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters.

We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters.