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目的了解肇庆市4家监测医院出生缺陷儿的发生率及其变化情况,研究出生缺陷发生的相关因素,为制定出生缺陷干预措施提供依据。方法按照《广东省出生缺陷医院监测方案》的要求,以市内4家医院作为监测医院,对肇庆市2001-2010年的出生缺陷监测资料进行回顾性分析。结果 2001-2010年共监测围产儿63476名,其中出生缺陷儿1034名,发生率为162.90/万,总体呈上升趋势,2010年的发生率比2001年高,差异有统计学意义(χ2=21.635,P<0.001)。前3位出生缺陷类型依次为先天性心脏病、胎儿水肿综合征、多指(趾)畸形。出生缺陷发生率与围产儿性别、孕母年龄、胎数有关。结论出生缺陷严重影响出生人口的素质,应继续加强三级预防措施,有效地降低出生缺陷的发生。
Objective To understand the incidence and changes of birth defects in four surveillance hospitals in Zhaoqing and to study the related factors of birth defects in order to provide evidence for the development of birth defects interventions. Methods According to the requirements of Guangdong Provincial Birth Defective Hospital Monitoring Program and 4 hospitals in the city as monitoring hospitals, the data of birth defects monitoring in 2001-2010 in Zhaoqing were retrospectively analyzed. Results A total of 63476 perinatal infants were detected in 2001-2010, of which 1034 were born with defective infants. The incidence rate was 162.90 / million, showing an overall upward trend. The incidence in 2010 was higher than that in 2001 (χ2 = 21.635 , P <0.001). The first three birth defects followed by congenital heart disease, fetal edema syndrome, multiple finger (toe) deformity. The incidence of birth defects and perinatal gender, maternal age, number of births. Conclusion Birth defects seriously affect the quality of the birth population. Three levels of prevention measures should be continuously strengthened to effectively reduce the incidence of birth defects.