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目的了解新疆维吾尔族艾滋病产妇利用预防艾滋病母婴传播综合干预措施落实情况并分析艾滋病母婴传播相关因素。方法本次研究严格按照知情同意,保密的原则在一个密封,安静,舒适的咨询室内进行一对一,面对面的问卷调查。结果在调查的182例HIV感染孕产妇中,孕前确诊HIV阳性122例,孕期发现37例,产时发现15例,产后发现8例。70例的产妇孕前进行过抗病毒治疗(X2=0.511,P=0.475>0.05),144例怀孕时进行过抗病毒治疗(X2=26.849,P<0.0001)。84.6%的新生儿服用了抗逆转录病毒药物(X2=21.026,P<0.0001),91.2%婴儿采用了人工喂养方式(X2=80.692,P<0.0001),182例阳性母亲所生婴儿中25例确诊为HIV阳性。结论预防艾滋病母婴传播措施能有效降低艾滋病母婴传播水平,通过为产妇提供预防艾滋病母婴传播干预服务,降低艾滋病母婴传播率,减少儿童的艾滋病新发感染。对各种可能的影响因素应予以充分重视,并有必要做进一步的研究。
Objective To understand the implementation of comprehensive interventions for preventing mother-to-child transmission of HIV / AIDS in Uyghur mothers in Xinjiang and to analyze the related factors of mother-to-child transmission of HIV. Methods The study conducted a one-on-one and face-to-face questionnaire survey in strict accordance with the principle of informed consent and confidentiality in a sealed, quiet and comfortable consultation room. Results Among the 182 HIV-infected pregnant women surveyed, 122 were confirmed positive for HIV before pregnancy, 37 were found during pregnancy, 15 were found during delivery and 8 were found during delivery. Seventy pregnant women received antiretroviral treatment before pregnancy (X2 = 0.511, P = 0.475> 0.05) and 144 were treated with antiviral therapy during pregnancy (X2 = 26.849, P <0.0001). 84.6% of newborns took antiretroviral drugs (X2 = 21.026, P <0.0001), 91.2% of infants were fed artificially (X2 = 80.692, P <0.0001), and 25 of 182 infants born to positive mothers Confirmed as HIV positive. Conclusion Prevention of mother-to-child transmission of HIV can effectively reduce the level of mother-to-child transmission of HIV / AIDS and reduce the mother-to-child transmission rate of HIV / AIDS and reduce the new HIV / AIDS infection in children by providing mother-to-child transmission prevention services to prevent malaria. All kinds of possible influencing factors should be given sufficient attention, and it is necessary to do further research.