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目的评价吸附全细胞百白破联合疫苗(DwPT)和吸附无细胞百白破联合疫苗(DaPT)临床不良反应发生情况,探讨防治和处置经验。方法按照国家规定的免疫程序和方法将百白破联合疫苗接种于健康适龄儿童,观察其临床反应发生情况。结果 DaPT接种不良反应发生率3.81%(57/1497)明显低于DwPT的23.46%(672/2865),两者有明显统计学意义。百白破联合疫苗随着接种次数的增多,发生不良反应情况也同样增多。结论 DaPT比DwPT接种安全性高,不良反应发生率低。接种前充分摇匀,深部肌肉注射,再次接种时更换接种位置,可以减少不良反应发生。
OBJECTIVE: To evaluate the clinical adverse reactions of combined Dopaglione (DwPT) vaccine and Daphnia coronatus (DaPT), and to explore the experience of prevention and treatment. Methods In accordance with the national immunization procedures and methods Baitai broken vaccine was vaccinated in healthy children of age, observe the clinical response to the situation. Results The incidence of DaPT vaccination was 3.81% (57/1497), which was significantly lower than that of DwPT (23.46%, 672/2865), both of which were statistically significant. Bupleurox combined vaccine with the increase in the number of vaccines, the occurrence of adverse reactions also increased. Conclusions DaPT is more safe to inoculate than DwPT and has a lower incidence of adverse reactions. Shake well before inoculation, deep intramuscular injection, re-vaccination vaccination position, can reduce adverse reactions.