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近几年来,已有一些关于筛选甲胎蛋白(AFP)进行肝细胞癌(HCC)早期诊断的报告,这对及时进行外科手术提高成活率已初步显示了它的作用。但是,在慢性肝炎和肝硬变(LC)病人中AFP的升高也并非少见。以前大多数作者认为,AFP是监测HCC有价值的实验,而很少注意到非恶性肝病AFP水平的变化。为此,本文对290例慢性HBV感染病人进行了1～4年随访,观察其AFP的动态变化。研究对象为290例慢性HBV感染病人(男203例、女87例),年龄为7～74岁(平均39.1岁)。无症状者190例(66%),其中
In recent years, there have been some reports on the early diagnosis of hepatocellular carcinoma (HCC) screening of AFP, which has initially shown its effect on timely surgical treatment to improve the survival rate. However, elevated AFP is not uncommon in patients with chronic hepatitis and cirrhosis (LC). Most authors previously thought that AFP was a valuable experiment for monitoring HCC and seldom noticed changes in the level of AFP in non-malignant liver disease. To this end, this article 290 cases of chronic HBV infection were followed up for 1 to 4 years to observe the dynamic changes of AFP. The study population consisted of 290 patients with chronic HBV infection (203 males and 87 females) aged 7-74 years (mean, 39.1 years). Asymptomatic 190 cases (66%), of which