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To compare the impact of oestrogen, gynaecological history, social support, li fe events and family history of CHD on psychosocial morbidity in syndrome X, CHD patients and healthy controls. 100 female syndrome X(60±9 years), 100 female C HD(65±9 years) and 100 healthy female volunteers(61±10 years) completed the ho spital anxiety and depression scale(HADS), health anxiety questionnaire (HAQ), a demographic information scale, life events scale, family history of CHD, menopa usal, menstrual and gynaecological history. A 17β oestradiol sample was taken. Syndrome X patients had higher levels of life interference(p< 0.05) and HADS an xiety(p < 0.05) than CHD patients, and higher levels of all HADS and HAQ scales than controls (p< 0.01). Syndrome X patients with a large social network had low er HADS anxiety (p< 0.05), health worry (p< 0.05), life interference (p< 0.01) a nd total HAQ(p< 0.01). Social network (p=0.003), divorced/separated or widowed s tatus(p=0.005),HRT (p=0.008) and HADS anxiety score(p< 0.001) accounted for 41.9 %of the variance in HAQ scores in syndrome X. Oestrogen was unrelated to the HA DS or HAQ for any group. Syndrome X patients suffered higher levels of psycholog ical morbidity in comparison to CHD patients and controls. Life events and socia l network size were related to health anxiety, general anxiety and depression in women with syndrome X.
To compare the impact of oestrogen, gynecological history, social support, li fe events and family history of CHD on psychosocial morbidity in syndrome X, CHD patients and healthy controls. 100 female syndrome X (60 ± 9 years), 100 female C HD ( 65 ± 9 years) and 100 healthy female volunteers (61 ± 10 years) completed the ho spital anxiety and depression scale (HADS), health anxiety questionnaire (HAQ), a demographic information scale, life events scale, family history of CHD, menopa Syndrome X patients had higher levels of life interference (p <0.05) and HADS an xiety (p <0.05) than CHD patients, and higher levels of all HADS and HAQ scales than controls (p <0.01). Syndrome X patients with a large social network had low er HADS anxiety (p <0.05), health worry (p <0.05), life interference ) Social network (p = 0.003), divorced / separated or widowed s tatus (p = 0.005), HRT (p = 0.008) and HA DS anxiety score (p <0.001) accounted for 41.9% of the variance in HAQ scores in syndrome X. Oestrogen was unrelated to the HA DS or HAQ for any group. Syndrome X patients suffered higher levels of psychological morbidity in comparison to CHD patients and controls. Life events and socia l network size were related to health anxiety, general anxiety and depression in women with syndrome X.