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甲孕酮(DMPA)和炔诺酮庚酸酯(NETEN)作为长效避孕针已广泛应用于临床,对它们的药代动力学和药效学已进行过研究,根据其结构特点,预计其代谢归宿和作用机制有区别,为此作者设计了DMPA和NET-EN在同一人群的比较研究,观察长期用药后排卵恢复的时间。作者选择24名墨西哥妇女,用药至少1.2年以上,分为两组,第一组14例,每隔90±7天肌注DMPA 150mg;第二组10例,头6个月每隔60±7天,此后每隔84±
Medroxyprogesterone acetate (NMP) and norethindrone acetate (NETEN) have been widely used clinically as long-acting injectables and their pharmacokinetics and pharmacodynamics have been studied. According to their structural characteristics, it is expected that Metabolic homeopathy and mechanism of action are different, for which the author designed DMPA and NET-EN in the same population of comparative study to observe the long-term use of ovulation recovery time. The authors selected 24 Mexican women, medication for at least 1.2 years, divided into two groups, the first group of 14 cases, every 90 ± 7 days intramuscularly DMPA 150mg; the second group of 10 cases, the first 6 months at 60 ± 7 Days, every 84 ± thereafter