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目的:探讨金水宝胶囊辅助治疗2型糖尿病肾病的临床疗效。方法:将136例2型糖尿病肾病患者随机分为对照组和观察组各68例,对照组采用常规治疗,观察组在此基础上加用金水宝胶囊口服,以12个月为一疗程,比较两组疗效及治疗前后24 h尿蛋白、肌酐及尿素氮变化。结果:观察组总有效率明显高于对照组(P<0.05);两组治疗后的24 h尿蛋白、肌酐及尿素氮均较治疗前明显下降(P<0.05);观察组治疗后24 h尿蛋白、肌酐及尿素氮下降较对照组明显(P<0.05)。结论:金水宝胶囊能提高2型糖尿病肾病患者的疗效,减缓患者的肾微血管病变,延缓肾功能不全的发生和发展。
Objective: To investigate the clinical effect of Jinshuibao capsule in adjuvant treatment of type 2 diabetic nephropathy. Methods: 136 patients with type 2 diabetic nephropathy were randomly divided into control group and observation group, with 68 cases in each group. The control group received routine treatment. The observation group was treated with Jinshuibao capsule orally on the basis of 12 months. The curative effect of two groups and the change of urinary protein, creatinine and urea nitrogen 24 h before and after treatment. Results: The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The 24 h urine protein, creatinine and urea nitrogen in the two groups were significantly decreased (P <0.05) 24 h after treatment Urinary protein, creatinine and urea nitrogen decreased significantly compared with the control group (P <0.05). Conclusion: Jinshuibao capsule can improve the curative effect of patients with type 2 diabetic nephropathy, relieve the patients’ renal microangiopathy and delay the occurrence and development of renal insufficiency.