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目的:评价重组人干扰素α-2b阴道泡腾胶囊在宫颈糜烂治疗中的应用效果。方法:2014年2月~2016年8月,医院门诊收治宫颈糜烂患者84例入组,采用抽签法分组,对照组、观察组各42例。分别采用聚甲酚磺醛溶液冲洗、重组人干扰素α-2b阴道泡腾胶囊治疗,3个月经周期,对比疗效、复发情况。结果:观察组痊愈率85.7%高于对照组73.8%,复发率2.4%低于对照组19.0%,差异有统计学意义(P<0.05)。治疗后,观察组与对照组症状积分低于治疗前,观察组低于对照组,差异有统计学意义(P<0.05)。结论:重组人干扰素α-2b阴道泡腾胶囊治疗宫颈糜烂疗效肯定。
Objective: To evaluate the effect of recombinant human interferon α-2b vaginal effervescent capsules in the treatment of cervical erosion. Methods: From February 2014 to August 2016, 84 outpatients with cervical erosion were enrolled in the outpatient department of the hospital. The patients were divided into two groups according to the method of drawing lots, the control group and the observation group. Respectively using polyphenol sulfonic acid solution rinse, recombinant human interferon α-2b vaginal effervescent capsules treatment, three menstrual cycles, the efficacy and recurrence. Results: The cure rate in the observation group was 85.7% higher than that in the control group (73.8%), the recurrence rate was 2.4% lower than that in the control group (19.0%), the difference was statistically significant (P <0.05). After treatment, symptom score in observation group and control group was lower than that before treatment, and the observation group was lower than that in control group, with significant difference (P <0.05). Conclusion: Recombinant human interferon α-2b vaginal effervescent capsules for the treatment of cervical erosion with certain effect.