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本研究评价按疾病管理和预防中心(Centers for Disease Control and Preven-tion,CDC)推荐的方法治疗妊娠期梅毒、根除母体感染和预防先天性梅毒的功效。 Ⅰ期、Ⅱ期或早潜伏期梅毒以2 400 000单位苄星青霉素(benzathine penicillin G)肌肉注射。晚潜伏期梅毒7 200 000单位苄星青霉素肌肉注射,连续3周以上。门诊检查和分娩时每月一次测定VDRL(veneral diseaseresearch laboratory test)滴度。Ⅰ期和Ⅱ期梅毒治愈标准为患者症状消失,滴度下降4倍3～4个月以上。潜伏期梅毒患者滴度下降4倍6个月以上可考虑为临床治愈。治疗失败为持续1个月以上滴度增加4倍或治疗6个月后滴度无变化。确定的先天感染病例需
This study evaluated the efficacy of treatment of gestational syphilis, eradicating maternal infection and preventing congenital syphilis as recommended by the Centers for Disease Control and Prevention (CDC). Stage I, II or early latent syphilis was intramuscularly injected with 2,400,000 benzathine penicillin G. Late latent syphilis 7 200 000 Units Benzathine penicillin intramuscularly for more than 3 weeks. VDRL (veneral disease research laboratory test) titer is determined monthly at outpatient examinations and at delivery. Symptoms of stage I and stage II syphilis were cured and the titer dropped 4-fold over 3 to 4 months. Latent syphilis patients titers dropped 4 times more than 6 months can be considered for clinical cure. The treatment failed for a duration of more than 1 month 4-fold increase in titer or 6 months after treatment, no change in titer. Confirmed cases of innate infections need