论文部分内容阅读
目的:探讨经肛门局部切除治疗直肠癌的疗效。方法:回顾性分析我院2005年7月~2012年7月收治的50例直肠癌患者给予肛门局部切除术后的临床疗效。结果:本组患者手术时间为35~90分钟,平均55分钟;术中出血量15~120ml,平均50ml;住院时间3~10天,平均5天;术后复发率21.3%,5年生存率91.7%,T1期术后复发率18.6%,T2期复发率24.8%,但是T1期和T2期2组术后复发率比较差异无统计学意义。高分化腺癌术后复发率13.2%,中分化腺癌为48.9%,高分化腺癌和中分化腺癌2组术后复发率比较存在显著性差异。肿瘤直径<3cm术后复发率9.9%,≥3cm复发率42.6%,肿瘤直径<3cm组和≥3cm组术后复发率比较存在显著性差异(P<0.05)。结论:对T1、T2期的高分化、肿瘤直径<3cm的直肠癌患者,实施经肛门局部切除术可取得良好的治疗效果,值得临床推广应用。
Objective: To investigate the effect of transrectal partial resection of rectal cancer. Methods: A retrospective analysis of our hospital from July 2005 to July 2012 in 50 cases of rectal cancer patients given anal partial resection of the clinical efficacy. Results: The operation time of this group was 35 to 90 minutes with an average of 55 minutes. The blood loss was 15 ~ 120ml with an average of 50ml. The hospital stay was 3 to 10 days with an average of 5 days. The recurrence rate was 21.3% and the 5-year survival rate 91.7%. The recurrence rate was 18.6% in T1 stage and 24.8% in T2 stage. However, there was no significant difference in the recurrence rate between T1 and T2. The recurrence rate of well-differentiated adenocarcinoma was 13.2% and that of moderate-differentiated adenocarcinoma was 48.9%. There were significant differences in the recurrence rates between well-differentiated adenocarcinoma and moderately differentiated adenocarcinoma. The tumor recurrence rate was 9.9% and 42.6% respectively when the diameter of tumor was less than 3 cm and less than 3 cm (P <0.05). Conclusion: For patients with well-differentiated T1 and T2 tumors with rectal cancer whose tumor diameter is less than 3 cm, partial anal resection can achieve good therapeutic effect and is worthy of clinical application.