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贵刊于1980年第1期43页刊登的“酚妥拉明试验引起死亡”一文中,作者提出酚妥拉明试验有一定危险性,特别是对严重动脉硬化患者,这是可贵的意见。但文中说到,患者转院前在酚妥拉明试验引起血压下降的抢救过程中首先应用了肾上腺素、正肾上腺索等,转院后又先后使用多巴胺、异丙肾上腺素等。我们认为,酚妥拉明是属于α-型抗肾上腺素类药物(α-型受体阻断药),用药后与α-型受体结合,如再使用肾上腺素,则不能使皮肤、粘膜,特别是内脏血管收缩引起升压反应,而仅表现为兴奋β受体的作用,主要是对骨骼肌血管的舒张作用。此时,肾上腺
In your article “Phentolamine Test-Induced Death” published on page 43 of Issue 1, 1980, No. 1, the author states that the phentolamine test is somewhat dangerous, especially for those with severe arteriosclerosis. However, the article said that before the transfer of patients in the phentolamine test caused by the decline in blood pressure during the rescue first applied epinephrine, adrenal cord and so on, transfer has successively used dopamine, isoproterenol and so on. We believe that phentolamine belongs to the class of α-type anti-adrenergic drugs (α-type receptor blocker), after treatment and α-type receptor binding, such as the use of epinephrine, you can not make the skin, mucosa , Especially vasoconstrictive vasoconstriction caused by the vasopressor response, but only showed the role of excited beta receptors, mainly on the relaxation of skeletal muscle blood vessels. At this point, the adrenal glands