High concentrations of human β-defensin 2 in gastric juice of patients with Helicobacter pyloriinfec

• 作 者: Hajime Isomoto Hiroshi Mukae H
• 机 构: SecondDepartmentofInternalMedicine,DepartmentofMolecularPathology,DepartmentofBacteriology,ThirdDepa
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2005年31期
• 关键词: Β-防御素2 胃液 胃疾病 幽门螺杆菌 细菌感染 β-defensin 1 β-defensin 2 Helicobacterpylori

AIM: Human β-defensin (HBD)-1 and HBD-2 are endogenous antimicrobial peptides. Unlike HBD-1, the HBD-2 expression is augmented by Helicobacter pylori (H pylori). We sought to determine HBD-1 and HBD-2 concentrations in gastric juice duringH pylori infecti