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目的探讨降低纤维蛋白原治疗急性脑梗死的临床疗效及预后分析。方法对收治的急性脑梗死患者100例按入院时间随机分为实验组和对照组各50例,2组均采用常规治疗,同时合理控制血压,降低颅内压及其合并症和有关并发症的处理,疗程均2周;活血化瘀药采用血栓通600mg加入0.9%氯化钠注射液250ml中静脉滴注,每日1次;实验组在此基础上应用蕲蛇酶注射液0.75U,加入0.9%氯化钠注射液250ml静脉滴注,每日1次,连用10d;治疗前后均行纤维蛋白原浓度、血粘度等实验室检查,观察临床疗效。结果实验组疗效明显优于对照组(P<0.05)。结论降低纤维蛋白原治疗可改善脑梗死患者。
Objective To investigate the clinical effects and prognosis of fibrinogen in the treatment of acute cerebral infarction. Methods One hundred patients with acute cerebral infarction admitted to our hospital were randomly divided into experimental group and control group (n = 50). All the two groups were treated by conventional therapy. At the same time, blood pressure was decreased and intracranial pressure and its complication and related complications were reduced Treatment, treatment were 2 weeks; blood circulation drugs using thrombus 600mg 0.9% sodium chloride injection 250ml intravenous infusion, once daily; experimental group on the basis of the application of acutaneous enzyme injection 0.75U, adding 0.9% sodium chloride injection 250ml intravenous infusion, once daily, once every 10d; before and after treatment were performed fibrinogen concentration, blood viscosity and other laboratory tests to observe the clinical efficacy. Results The experimental group was significantly better than the control group (P <0.05). Conclusions Reducing fibrinogen can improve patients with cerebral infarction.