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目的分析邢台市麻疹减毒活疫苗(MV)强化免疫效果,探讨加速控制麻疹策略。方法分析麻疹减毒活疫苗强化免疫前后抗体滴度的变化。结果麻疹强化免疫共接种目标儿童1006243名,报告接种率和快速评估接种率均在98%以上。强化免疫后人群麻疹IgG抗体阳性率、抗体几何平均滴度均显著升高,麻疹发病率较强化免疫前明显下降。结论邢台市麻疹强化免疫效果显著,高质量强化免疫是迅速控制麻疹流行,降低麻疹发病率的重要措施。为保持麻疹强化免疫取得的成果,必须提高常规免疫接种率,及时查漏补种,减少易感人群的积累,提高易感人群的麻疹抗体水平。
Objective To analyze the effect of boosting live attenuated measles vaccine (MV) in Xingtai City and to explore the strategy of accelerating measles control. Methods The changes of antibody titers before and after intensive immunization of live attenuated measles vaccine were analyzed. Results 1006243 children were vaccinated with intensive immunization, and the reported vaccination rate and rapid assessment vaccination rate were above 98%. After immunization, the positive rate of measles IgG antibody and the geometric mean antibody titer were all significantly increased, and the incidence of measles was significantly lower than that before immunization. Conclusion The measles immunity in Xingtai City is significant. The high quality intensive immunization is an important measure to control the epidemic of measles quickly and reduce the incidence of measles. In order to maintain the results of measles-based immunization, it is necessary to increase the routine immunization rate, timely leak detection and replanting, reduce the accumulation of susceptible populations and raise the level of measles antibodies in susceptible populations.