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奎尼丁治疗是获得性长QT综合征(简称LQTS)最常见的原因之一、该综合征以显著QT延长和特征性的多形性室性心动过速为特点、后者又称为扭转型室速(Tdp)、作者回顾性研究了一组奎尼丁相关的LQTS,对一些迄今为人忽视或尚未认识的临床问题提出了见解、方法:选择在奎尼丁治疗期间的QT≥600毫秒者共24例,不包括单纯QTe延长者、Tdp定为奎尼丁治疗过程中,有QT延长时发生的连续5跳以上的多形性室速,且于停药后消失、对所记录的TdB心电图作以下分析:①发作前心动周期,②发作起始配对间期,③发作起始的Q-T峰间期,与10名奎尼
Quinidine is one of the most common causes of Acquired Long QT Syndrome (LQTS), which is characterized by significant QT prolongation and characteristic pleomorphic ventricular tachycardia, also known as twisting Tdp, we retrospectively reviewed a panel of quinidine-related LQTS that sheds new light on some of the clinical issues that have so far been overlooked or have not been identified by selecting a QT ≥600 millisecond during quinidine treatment A total of 24 patients, excluding pure QTe extenders, Tdp scheduled for quinidine treatment, there QT extension occurred more than 5 consecutive pleomorphic ventricular tachycardia and disappeared after withdrawal, the recorded TdB electrocardiogram for the following analysis: ① pre-attack cardiac cycle, ② onset paired interphase, ③ onset of QT peak interphase, and 10 Quinni