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冠状血管内注射链激酶治疗因血栓所致的急性心肌梗塞,其疗效已被公认。本文旨在比较通过冠状血管内或静脉内注射链激酶治疗急性心肌梗塞的疗效。方法:51例疑有急性心肌梗塞而经紧急冠状血管及左室造影证实有冠状血管系统部份或完全闭塞的病人,随机分为两组。25例(男22例,女3例)在冠状血管内注射链激酶(简称冠脉组);26例(男19例,女7例)在周围静脉内注入链激酶(简称静脉组)。冠脉组先在梗塞有关动脉口注入硝酸甘油200微克,然后将链激酶24万单位加在240毫升的生理盐水中,一部份病人以400单位/分的速度用泵注射,另一部份则每15秒推注1毫升。少数病人加
The efficacy of coronary injections of streptokinase in the treatment of acute myocardial infarction due to thrombosis has been well established. This article aims to compare the efficacy of streptokinase administered intracoronary or intravenously to treat acute myocardial infarction. Methods: Fifty-one patients with suspected acute myocardial infarction who had partial or complete occlusion of coronary vasculature by emergency coronary and left ventricular angiography were randomly divided into two groups. Twenty-five patients (22 males and 3 females) were injected with streptokinase (abbreviated as coronary artery group) in coronary vessels. In 26 patients (19 males and 7 females), streptokinase (abbreviated as vein group) was injected into the peripheral vein. In the coronary artery group, 200 micrograms of nitroglycerin was infused into the arterial ostia of the infarct, 240,000 streptokinase was then added to 240 microliters of normal saline, and some of the patients were injected with a pump at a rate of 400 units / min. The other part 1 ml is bolted every 15 seconds. A small number of patients plus