Doublecortin-like kinase 1 exhibits cancer stem cell-like characteristics in a human colon cancer ce

• 作 者: Lianna Li Charles E Bellows
• 机 构: DepartmentofSurgery,UniversityofMississippiCancerInstitute
• 出 处: 中国癌症研究：英文版
• 发表日期: 2013年2期
• 关键词: 肿瘤干细胞 细胞株 结肠癌 特性 激酶 无血清培养基 自我更新能力 蛋白质水平 Doublecortin-like kinase 1 （DCLK1） color
• 基金项目: We＇d like to thank The Louisiana Cancer Research Consortium FACS Core for providing the FACS service. Disclosure： The authors declare no conflict of interest.

Purpose: Colon cancer stem cells (CSCs) are implicated in colorectal cancer carcinogenesis, metastasis, and therapeutic resistance. The identification of these cells could help to develop novel therapeutic strategies. Doublecortin-like kinase 1 (DCLK1) ha