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为探讨慢性阻塞性肺部疾病与心率变异性的关系 ,对24例慢性阻塞性肺部疾病和24例对照组进行心率变异性分析 ,并观察其与第1s用力呼气量的相关性。结果显示 :慢性阻塞性肺部疾病患者的SDNN、SDANN、SDNNIndex、rMSSD、PNN50 均明显低于对照组 (P<0.05) ,且第1s用力呼气量与上述时域指标呈高度正相关 (r=0.61～0.89,P<0.01)。提示心率变异时域指标反映慢性阻塞性肺部疾病的严重程度 ,有临床参考意义。
To explore the relationship between chronic obstructive pulmonary disease and heart rate variability, 24 patients with chronic obstructive pulmonary disease and 24 control subjects were analyzed for heart rate variability, and their correlation with forced expiratory volume at 1s was also observed. The results showed that the SDNN, SDANN, SDNN Index, rMSSD and PNN50 in patients with chronic obstructive pulmonary disease were significantly lower than those in the control group (P <0.05), and the forced expiratory volume at 1s was highly correlated with the above time domain indexes = 0.61 ~ 0.89, P <0.01). Prompted heart rate variability time domain index reflects the severity of chronic obstructive pulmonary disease, a clinical reference value.