Highly efficient and easy synthesis of 2,4,6-triarylpyridines catalyzed by pentafluorophenylammonium

• 作 者: Naser Montazeri Saber Mahjoob
• 机 构: Department of Chemistry,Faculty of Sciences,Tonekabon Branch,Islamic Azad University,
• 出 处: Chinese Chemical Letters
• 发表日期: 2012年04期
• 关键词: Pentafluorophenylammonium triflate 2 4 6-Triarylpyridines Solvent-free condition

Pentafluorophenylammonium triflate(PFPAT) was found to be a highly efficient catalyst for the preparation of 2,4,6- triarylpyridines from the reaction of acetophenone derivatives,aromatic aldehydes and ammonium acetate.Present methodology offers several advantages,such as short reaction time,high yields,simple procedure with an easy work-up and the absence of any volatile and hazardous organic solvent.In addition,this catalytic system can act as an active,inexpensive,metal-free,recoverable and recyclable catalyst.

Pentafluorophenylammonium triflate (PFPAT) was found to be a highly efficient catalyst for the preparation of 2,4,6-triarylpyridines from the reaction of acetophenone derivatives, aromatic aldehydes and ammonium acetate. Present methodology offers several advantages, such as short reaction time, high yields, simple procedure with an easy work-up and the absence of any volatile and hazardous organic solvent. In addition, this catalytic system can act as an active, inexpensive, metal-free, recoverable and recyclable catalyst.