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目的观察静脉输注人血丙种球蛋白和地塞米松联合治疗小儿特发性血小板减少性紫癜 (ITP)的疗效。方法观察静脉输注人血丙种球蛋白和地塞米松联合治疗、仅输注人血丙种球蛋白、仅输注地塞米松后血小板计数变化和维持时间。结果三组疗效无显著性差异 (P>0 .0 5 ) ,但三组用药后一周内血小板上升速度及血小板升至正常后持续时间却有差异。结论人血丙种球蛋白和地塞米松联合治疗 ITP能迅速有效地控制重要器官如颅内等免于出血 ,不需重复用药 ,值得在临床推广应用
Objective To observe the efficacy of intravenous infusion of human gamma globulin and dexamethasone in the treatment of idiopathic thrombocytopenic purpura (ITP) in children. Methods The intravenous infusion of human gamma globulin and dexamethasone combined treatment, only the infusion of human blood gamma globulin, only after infusion of dexamethasone platelet count changes and maintenance time. Results There was no significant difference in efficacy between the three groups (P> 0.05). However, there was a difference in the platelet rise rate and the platelet rise duration after one week. Conclusion The combination of human gamma globulin and dexamethasone in the treatment of ITP can rapidly and effectively control important organs such as intracranial hemorrhage without repeated medication, which is worthy of clinical application