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目的 :探讨重型肝炎的死亡原因及主要并发症 ,进一步提高存活率。方法 :对 15 4例重型肝炎的死亡原因及主要并发症进行分析。结果 :重型肝炎的死亡率仍以慢性乙型肝炎为主。直接死亡原因以肝肾综合征最高(36 .36 % ) ,其次为严重感染 (2 8.5 7% )、上消化道大出血 (2 1.4 3% )、肝功能衰竭伴肝性脑病、脑水肿(10 .0 9% )。结论 :降低重型肝炎的死亡率首先做好预防 ,减少乙型肝炎的感染率。早期阻止免疫病理和肠源性的内毒素继发性损伤 ,积极预防和治疗各种并发症 ,是减少重型肝炎死亡率的关键。
Objective: To investigate the causes of death and major complications of severe hepatitis to further improve the survival rate. Methods: The causes of death and major complications of 15 4 cases of severe hepatitis were analyzed. Results: The mortality rate of severe hepatitis was still mainly chronic hepatitis B The direct cause of death was hepatorenal syndrome (36.36%), followed by severe infection (2.857%), upper gastrointestinal bleeding (2.14%), hepatic failure with hepatic encephalopathy, cerebral edema .0 9%). Conclusion: To reduce the mortality rate of severe hepatitis, we should take precautions to reduce the infection rate of hepatitis B first. Early prevention of immunopathology and intestinal endotoxin secondary injury, and actively prevent and treat various complications, is the key to reduce the mortality of severe hepatitis.