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目的探讨氯沙坦联合灯盏花素片治疗慢性肾小球肾炎的临床疗效。方法 100例慢性肾小球肾炎患者,随机分为对照组及研究组,各50例。对照组应用氯沙坦治疗,研究组应用氯沙坦联合灯盏花素片治疗。比较两组患者临床疗效及不良反应发生情况。结果研究组总有效率96.0%高于对照组82.0%,差异具有统计学意义(χ~2=5.005,P=0.025<0.05)。研究组不良反应发生率为4.0%,对照组不良反应发生率为6.0%,对比差异无统计学意义(χ~2=0.211,P=0.646>0.05)。结论慢性肾小球肾炎应用氯沙坦联合灯盏花素片治疗能够获得较好临床疗效,安全性高,值得临床推广。
Objective To investigate the clinical efficacy of losartan combined with breviscapine in the treatment of chronic glomerulonephritis. Methods One hundred patients with chronic glomerulonephritis were randomly divided into control group and study group, 50 cases each. The control group was treated with losartan, and the study group was given losartan combined with breviscapine tablet. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate was 96.0% in the study group and 82.0% in the control group (χ ~ 2 = 5.005, P = 0.025 <0.05). The adverse reaction rate was 4.0% in the study group and 6.0% in the control group. There was no significant difference between the two groups (χ ~ 2 = 0.211, P = 0.646> 0.05). Conclusion The treatment of chronic glomerulonephritis with losartan combined with breviscapine tablets can achieve better clinical efficacy, which is safe and worthy of clinical promotion.