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收集100例术中胆囊或胆管胆汁进行细菌培养、测免疫球蛋白(Ig)含量,并测血清Ig含量,及34例胆囊组织匀浆Ig含量。结果表明胆道感染患者血清中三类Ig含量极显著高于正常人(n=100,P<0.01)。胆汁培养阳性组血清IgA显著高于阴性组(P<0.01)。胆汁培养单一菌种生长时血清IgA高于2种以上细菌生长,其余Ig含量在胆汁培养1～3种细菌生长,或草兰氏阴性杆菌或阳性球菌时差异均无显著性(P>0.05),胆汁培养阳性组胆囊汁中IgG高于胆管胆汁;阴性组胆管胆汁中IgG高于胆囊胆汁。胆囊胆汁培养阳性组胆囊胆汁中三类Ig含量均高于胆囊组织匀浆;阴性组其IgG和IgM高于胆囊组织匀浆,而IgA无明显相关关系。
100 cases of intraoperative gallbladder or bile duct bile bacterial culture, measuring the content of immunoglobulin (Ig) and serum Ig content, and 34 cases of gallbladder tissue homogenate Ig content. The results showed that the contents of three kinds of Ig in serum of patients with biliary tract infection were significantly higher than those of normal people (n = 100, P <0.01). Serum IgA in bile culture positive group was significantly higher than that in negative group (P <0.01). There was no significant difference between the two groups when the serum IgA of bile culture was higher than that of more than two kinds of bacteria. The other Ig contents did not show any significant difference (P> 0.05) between 1 ~ 3 kinds of bacteria growth in bile culture or those of gram-negative bacilli or cocci. , IgG positive in bile culture positive group was higher than that in bile duct, IgG in bile duct was higher than that in gallbladder in negative group. Gallbladder bile culture positive group gallbladder bile in the three levels were higher than gallbladder homogenate; negative group IgG and IgM higher than gallbladder tissue homogenate, while IgA no significant correlation.