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目前,国内外对乳腺癌的有关基因表达的大量研究表明,CD24、CD44参与了乳腺癌的浸润、转移过程,增殖细胞核抗原(PCNA)被认为是乳腺癌的重要预后因子。相关研究主要涉及CD24、CD44及PCNA的生物学特性、各自与乳腺癌的关系等,目的在于分析三者联合检测对乳腺癌的影响,对CD24、CD44及PCNA在乳腺癌的发生和发展、增殖及转移的机制方面作更加深入的研究,以进一步研究证实三者的联合检测对乳腺癌的治疗及预后是否可提供临床参考价值等。
At present, a large number of studies on breast cancer gene expression at home and abroad show that CD24 and CD44 are involved in the infiltration and metastasis of breast cancer, and PCNA is considered as an important prognostic factor for breast cancer. Related studies mainly related to the biological characteristics of CD24, CD44 and PCNA, their relationship with breast cancer, the purpose is to analyze the combined detection of breast cancer, the CD24, CD44 and PCNA in the occurrence and development of breast cancer, proliferation And metastasis mechanism for more in-depth study to further study confirmed that the three joint detection of breast cancer treatment and prognosis can provide clinical reference value.