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目的 评价非离子型造影剂iopromide(370 ) (优维显 370 )和离子型造影剂 76 %diatrizoate(76 %优路芬 )对冠状动脉造影时QT离散度参数的影响。方法 6 0例行冠状动脉造影的患者 ,男 4 1例 ,女 19例 ;年龄 (5 4± 11)岁。随机分为优维显组和优路芬组 ,采用Judkins法行冠状动脉造影。记录冠状动脉造影前和左、右侧冠状动脉第一次注射造影剂后连续 2 5秒的 12导联体表心电图 ,然后计算QT离散度。结果 左冠及右冠注入优维显、优路芬 10秒及2 0秒后 ,QT间期、QTc明显延长 ,但对QTd和QTcd均无明显影响。结论 冠脉造影时 ,优维显和优路芬对QT离散度无明显影响。
Objective To evaluate the effect of nonionic contrast agent iopromide (370) and ionotropic contrast agent 76% diatrizoate on QT dispersion parameters during coronary angiography. Methods Sixty-two male patients (19 males and 19 females, aged 54 ± 11 years) underwent routine coronary angiography. Randomly divided into Youve significant group and Youlufen group, using the method of Judkins coronary angiography. The 12-lead body surface electrocardiogram was recorded before coronary angiography and the left and right coronary arteries were injected for the first time after contrast medium injection, and QT dispersion was calculated. Results After the left and right coronary arteries were infused with Uvoxian and Youlufen for 10 seconds and 20 seconds, QTc and QTc were prolonged significantly, but no significant effect was found on QTd and QTcd. Conclusions Coronary angiography showed that vinyloxine and flusulfide had no significant effect on QT dispersion.