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目的探讨超声检测外周动脉粥样硬化情况和内皮功能对冠状动脉血管病变的临床预测价值。方法应用彩色多普勒超声对72例健康者及56例明确冠状动脉病变患者的颈动脉内-中膜厚度(carotid inti-ma-media thickness,CIMT)、股动脉内-中膜厚度(femoral intima-media thickness,FIMT)及肱动脉内皮功能进行检测,比较两组的检测结果并进行统计学分析。结果冠状动脉病变组患者的CIMT、FIMT值均高于健康组(P<0.05),其颈动脉、股动脉粥样斑块检出率明显升高,而肱动脉内皮依赖性舒张功能(flow-mediated dilation,FMD)明显低于健康对照组(P<0.05)。结论超声检查外周血管可以预测冠状动脉病变,该检测方法具有无创、精确、方便、快捷等优势,可以作为预测冠脉病变的首选方法。
Objective To investigate the clinical value of ultrasound in the detection of peripheral atherosclerosis and endothelial function in patients with coronary artery disease. Methods Color Doppler echocardiography was used to evaluate carotid intima-media thickness (CIMT), femoral intima (femoral intima-media thickness) in 72 healthy subjects and 56 patients with definite coronary lesions -media thickness (FIMT)) and brachial artery endothelial function were compared. The results of the two groups were compared and statistically analyzed. Results The CIMT and FIMT values in patients with coronary artery disease were significantly higher than those in healthy subjects (P <0.05). The detection rates of carotid artery and femoral artery atherosclerotic plaques were significantly increased, while those of flow- mediated dilation (FMD) was significantly lower than the healthy control group (P <0.05). Conclusion Peripheral blood vessels can be used to predict coronary artery disease by ultrasonography. This method is noninvasive, accurate, convenient and quick. It can be used as the first choice to predict coronary artery disease.