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生物、化学及核武器等特殊战争条件下皮肤损伤的机理研究及防护,是近年来军事医学皮肤病学的重点研究内容。芥子气是一种强效糜烂性化学武器成分,战时和平时均可对军队和群众造成持久的威胁。急性芥子气皮肤损伤表现为急性刺激症状如刺痛、瘙痒和灼烧感,红斑、水疱、溃疡等;慢性皮肤损伤包括皮肤斑丘疹、色素沉着或减退、干燥、萎缩、瘢痕以及对机械刺激敏感增强、周期性的水疱和溃疡形成等。目前,药物治疗已经成为急性和慢性芥子气接触后缓解及治疗临床症状的主要方式,如新型药物水飞蓟宾及多种药物(白藜芦醇和bFGF)的联合使用。
Biological, chemical and nuclear weapons and other special warfare conditions of skin damage mechanism of research and protection, military medical dermatology in recent years, the focus of research. Mustard gas is a potent and erosive chemical weapon that can endanger the military and the masses in peacetime and in peacetime. Acute mustard gas skin lesions are characterized by acute irritation such as tingling, itching and burning sensation, erythema, blisters, ulcers and the like; chronic skin lesions including cutaneous rash, pigmentation or diminution, dryness, atrophy, scarring and sensitivity to mechanical stimulation , Periodic blisters and ulcer formation. At present, drug therapy has become the main way to relieve and treat clinical symptoms after acute and chronic mustard exposure, such as the combination of a new drug, silybin, and various drugs (resveratrol and bFGF).