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目的了解乌鲁木齐地区医疗卫生机构二级生物安全实验室的现状、存在的问题,为新疆地区实验室的生物安全提供参考。方法对乌鲁木齐地区26家医疗卫生机构的二级生物安全实验室进行调查,组织专家进行现场查验及实验室相关资料审核,填写统一检查表并附整改意见,再对资料进行统计描述。结果 26家医疗卫生机构均设有安全管理委员会,实验室设施设备合格率高,但仍存在标识不符等问题;生物安全柜、高压蒸汽灭菌器的使用率高,然而其年检报告不合格率分别为42.42%和30.30%。意外事故应急能力方面存在问题较多,如无危害评估报告、实验活动风险评估报告、意外事故处理程序和SOP,其中无紧急撤离路线的最高占31.82%;菌毒种及样本存在问题的占15.15%。结论乌鲁木齐地区医疗卫生机构生物安全实验室设施设备基本达到要求,然而管理体系仍需进一步完善。意外事故应急能力、菌毒种管理方面仍需大力加强,为新疆地区实验室的生物安全做出贡献。
Objective To understand the status quo and existing problems of secondary biosafety laboratories in medical and health institutions in Urumqi and to provide references for the biosafety of laboratories in Xinjiang. Methods To investigate the secondary biosafety laboratories of 26 medical and health institutions in Urumqi, organize experts to conduct on-site inspection and laboratory-related data review, fill in the unified inspection form and attach rectification, and then describe the data statistically. Results There were safety management committees in 26 medical and health institutions with high pass rate of laboratory facilities and equipment, but there were still some problems such as inconsistent marks. The biological safety cabinets and high-pressure steam sterilizers had a high utilization rate. However, the annual inspection report failed rate Respectively 42.42% and 30.30%. There are many problems in accident emergency response capability, such as no hazard assessment report, risk assessment report of experimental activities, accident handling procedures and SOP, of which 31.82% is the highest without emergency evacuation routes and 15.15 %. Conclusion The facilities and facilities of biosafety laboratories in medical and health institutions in Urumqi basically met the requirements. However, the management system still needs to be further improved. Accident emergency response capacity, the management of bacterial species still need to be vigorously strengthened, to contribute to the biological safety of laboratories in Xinjiang.