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随着科学和医学基础研究的进展,在皮肤科领域内无论在临床、基础理论、治疗方法、以及各种新药物的出现等等,各方面都有很大改观,在此由于水平及阅读材料所限,不能全面概述,重点谈谈大疱性皮肤病的进展。近年来由于免疫荧光等技术的应用,对大疱性皮肤病的研究有了显著进步,特别是对诊断、治疗及发病机理方面的了解。在大疱性皮肤病中属于自身免疫疾病的天疱疮及大疱性类天疱疮均已证明了其不同的抗体,前者有抗表皮细胞间(膜)抗体,后者有抗基底膜部抗体,这对阐明疾病的本质有了进一步认识。
With the progress of the basic research in science and medicine, there has been a great improvement in the field of dermatology, both in clinical practice, basic theory, treatment methods, and the emergence of various new drugs. Since the level and reading materials Limited, can not be a comprehensive overview, focusing on the progress of bullous skin disease. In recent years due to the application of immunofluorescence and other technologies, the study of bullous skin disease has made significant progress, especially in the diagnosis, treatment and pathogenesis of understanding. Pemphigus and bullous pemphigus, which are autoimmune diseases in bullous dermatosis, have all been shown to have different antibodies, the former having anti-epidermal cell (membrane) antibodies and the latter having anti-basal membrane sections Antibodies, which further elucidate the nature of the disease.