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目的建立兔眼外伤性近视的动物模型,对相关指标作出检测,从检测结果中分析引起眼外伤性近视的各项因素的意义。方法建立兔眼钝挫伤模型。进行外伤前后眼轴长度、角膜厚度、屈光状态、前房深度、晶体厚度等指标的检测,并统计分析各项指标的意义。结果外伤后1d与外伤前比较,眼轴长度、角膜厚度(瞳孔区)、前房深度、晶体厚度的改变都具有统计学意义(P<0.05),但在外伤后7d,仅有晶体厚度的改变具有统计学意义(P<0.05)。活体超声生物显微镜及组织病理学显示:与外伤前相比,睫状体在外伤后存在着不同程度的水肿。结论在外伤后初期,各项指标的改变对外伤性近视起着共同的作用。但在后期可能只有睫状体及晶体的改变起着决定性作用。
Objective To establish an animal model of traumatic myopia in rabbit eyes and detect the related indexes. The significance of the various factors that cause ocular traumatic myopia is analyzed from the test results. Methods Rabbit eye contusion model was established. Before and after trauma, axial length, corneal thickness, refractive status, anterior chamber depth, crystal thickness and other indicators of detection, and statistical analysis of the significance of the indicators. Results The changes of axial length, corneal thickness (pupil area), anterior chamber depth and crystal thickness were statistically significant at 1 day after trauma compared with those before injury (P <0.05). However, at 7 days after trauma, only the thickness of the lens The changes were statistically significant (P <0.05). Biological ultrasound biomicroscopy and histopathology showed that compared with pre-trauma, the ciliary body had different degrees of edema after trauma. Conclusion In the early stage of trauma, the changes of various indexes play a common role in traumatic myopia. But in the latter may only ciliary body and crystal changes play a decisive role.