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目的:探讨奥曲肽联合凝血酶治疗肝硬化合并上消化道出血的疗效。方法:挑选我院所收治的54例肝硬化合并上消化道出血患者作为研究对象,分为对照组与观察组,每组27例。对比两组患者疗效、止血时间、再出血率与住院时长。结果:观察组总有效率为88.9%,明显比对照组74.0%要高。对比止血时间、输血量、住院时间,观察组优于对照组。观察组再出血率为7.4%,明显比对照组25.9%要低,差异有统计学意义(P<0.05)。结论:奥曲肽联合凝血酶治疗肝硬化合并上消化道出血的疗效显著,提高止血成率,减少再出血率,值得临床推广。
Objective: To investigate the efficacy of octreotide combined with thrombin in the treatment of cirrhosis and upper gastrointestinal bleeding. Methods: 54 cases of patients with cirrhosis complicated with upper gastrointestinal bleeding admitted to our hospital were selected as research object and divided into control group and observation group, with 27 cases in each group. The curative effect, hemostasis time, rebleeding rate and length of stay in two groups were compared. Results: The total effective rate in observation group was 88.9%, significantly higher than 74.0% in control group. Hemostatic time, blood transfusion, hospital stay, observation group than the control group. The rate of rebleeding in the observation group was 7.4%, which was significantly lower than that in the control group (25.9%), the difference was statistically significant (P <0.05). Conclusion: The effect of octreotide combined with thrombin in the treatment of cirrhosis and upper gastrointestinal hemorrhage is significant, and the rate of hemostasis and the rate of rebleeding are worthy of clinical promotion.