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目的：观察喉癌患者的白细胞介素2（IL—2）与可溶性白细胞介素2受体（sIL—2R）水平的变化．方法：IL—2测定采用IL—2诱生及活性测定法,sIL—2R采用双抗体夹心法。结果：喉癌患者IL—2水平明显低于对照组，经统计学处理差异显著（P＜0．01），而sIL—2R水平则显著增高（P<0．01），并且与喉癌的分型及分期有明显的相关性；结论：sI-2R水平测定配合IL—2测定可作为喉癌临床监测的重要指标。
Objective: To observe the changes of interleukin 2 (IL-2) and soluble interleukin 2 receptor (sIL-2R) in patients with laryngeal cancer. Methods: IL-2 was measured by IL-2 induction and activity assay, and sIL-2R was detected by double antibody sandwich method. Results: The level of IL-2 in laryngeal cancer patients was significantly lower than that in control group (P <0.01), while the level of sIL-2R was significantly increased (P <0.01) There was a significant correlation between classification and staging. Conclusion: The determination of sI-2R combined with IL-2 can be used as an important indicator of clinical monitoring of laryngeal cancer.