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目前认为弥漫性甲亢和慢性淋巴细性甲状腺炎的发病机理,极可能是与原发性免疫疾患有关。它们在遗传和发病机理上有特别紧密的联系。有关体液性免疫球蛋白的目前情况一、甲状腺自身抗体自从1956年发现血清的甲状腺抗体后,目前已发现在慢性淋巴细胞性甲状腺炎和弥漫性甲亢时都有各种甲状腺自身抗体,包括对甲状腺球蛋白的抗体、对甲状腺球蛋白以外的胶体成分的抗体、对甲状腺“微粒体”的抗体和抗核成分。这些抗体系由B淋巴细胞产生。最近有证据表明它们要与T淋巴细胞结合后才有细胞毒性。因此可能细胞免疫和体液性免疫两者对
At present, the pathogenesis of diffuse hyperthyroidism and chronic lymphocytic thyroiditis is most likely related to the primary immune disorder. They are particularly closely linked in genetics and pathogenesis. Current status of humoral immunoglobulin thyroid autoantibodies Thyroid antibodies have been found in serum since 1956 and have now been found to have various thyroid autoantibodies in chronic lymphocytic thyroiditis and diffuse hyperthyroidism including thyroid Antibodies to globin, antibodies to colloidal components other than thyroglobulin, antibodies to thyroid “microsomes”, and anti-nuclear components. These antibodies are produced by B lymphocytes. There is recent evidence that they have cytotoxicity when combined with T lymphocytes. It is therefore possible to pair both cellular and humoral immunity