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目的 探讨围手术期不输血完成食管癌切除术的可行性。方法 1996 年1 月1998 年3 月共施行食管鳞癌切除术615 例,将其分为两组,输血组:1996 年1 月1997 年1 月围手术期常规输血的食管癌手术患者279 例;不输血组:1997 年2 月1998 年3 月围手术期不输血食管癌手术患者336 例,比较两组的相关指标。 结果 输血组与不输血组比较,术中出血量,手术前后外周血血红蛋白含量,红细胞、血小板计数,出、凝血时间和术后感染性并发症的发生率均无差异( P> 0 .05) ;围手术期输血量差异有显著性( P< 0 .01) ;胸腔引流穿刺量输血组大于不输血组( P< 0-05) 。 结论 食管癌手术客观上存在不输血而顺利完成的可能性,围手术期不输血不影响食管癌手术质量及安全性。
Objective To investigate the feasibility of complete transesophageal resection without perioperative blood transfusion. Methods A total of 615 cases of esophageal squamous cell carcinoma resection were performed in January 1996 and March 1998. They were divided into two groups. The transfusion group consisted of 279 cases of esophageal cancer patients undergoing routine blood transfusions during the perioperative period in January 1996. In the non-blood transfusion group: 336 patients who did not undergo transfusion surgery for esophageal cancer during the perioperative period in February 1997 and March 1998, and the related indicators of the two groups were compared. Results There was no difference in blood loss, preoperative hemoglobin content, erythrocyte, platelet count, ejection and coagulation time, and postoperative infectious complications between the blood transfusion group and non-blood transfusion group (P> 0.05). Perioperative blood transfusion was significantly different (P < 0. 01); thoracic drainage puncture transfusion group was greater than non-transfusion group (P <0-05). Conclusion The objective of esophageal cancer surgery is objectively possible without blood transfusion. Perioperative non-transfusion does not affect the quality and safety of esophageal cancer surgery.